Abstract

Dr. Zoha Hashmi*, Dr. Tabassum Rasul and Dr. Anum Qureshi

ABSTRACT

Background: Urinary tract infection is common in all age groups. It is more common in females, immunocompromised patients and those who have been catheterized or had some other invasive procedure of urinary tract. Gram negative and gram positive microorganisms are responsible for UTI. Sensitivity of uropathogens to antimicrobial drugs has changed over the past many years. Objective: The present study was planned to determine the common uropathogens, their antimicrobial sensitivity and clinical profile at a tertiary level health facility. Material & Methods: In this cross sectional study, urine samples of two hundred symptomatic patients were studied and the underlying pathogens were identified by appropriate methods. The present study was conducted from January 2019 to July 2019 in Nishtar Medical University and Hospital, Multan. Subsequently their sensitivity to antibiotics was determined by the recommended method. The data was entered and analyzed in SPSS 15. Results: Female patients were more than males. Increased frequency and dysuria were observed in all patients. E.coli was the commonest pathogen identified, followed by Klebsiella, Staphylococcus and Pseudomonas species. E.coli was sensitive to aminoglycosides, carbapenem and quinolones in decreasing order of frequency. Klebseilla and pseudomonas are sensitive to norfloxacin, whereas, staphylococcus are sensitive to quinolones. Conclusion: E.coli remains the most common uropathogen. Antimicrobial sensitivity of uropathogens showed a changing pattern.