ISOTRETINOIN: A POTENTIAL TREATMENT FOR COVID-19
Ahmed M. Abbas*, Islam M. Ebrahim, Abdelrahman G. Ramadan and Alaa Rashad Ali
ABSTRACT
The emergence of coronavirus disease-2019 (COVID-19) pandemic and its catastrophic consequences resulted in extreme demand for treatment. Nevertheless, it requires a relatively long time to approve new drugs to be used on humans. Therefore, researchers are reconsidering widely available and already approved drugs to be used in the treatment of COVID-19. This review illustrates the promising effect of isotretinoin in the treatment of SARS-CoV-2 owing to its ability to reduce Angiotensin Converting Enzyme (ACE2) receptor expression and its impact on immunity, androgen receptors, and respiratory diseases.
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