A REVIEW ON DEXAMETHASONE AND ITS SIGNIFICANCE
Pavithran G., Anusha V. H. and Vyshnavi V. Rao*
ABSTRACT
Dexamethasone is a globally used corticosteroid in treatment rheumatic problems, skin diseases and cancers. It was first discovered by Philip Showalter Hench in 1957 and was approved for medicinal use in 1961. It is one among the list of essential medicines released by World Health Organization (WHO). National Institutes of Health (NIH), US and National Health Service, UK have recommended use of Dexamethasone in patients with severe COVID-19 symptoms and are on external oxygen supply. This article aims to discuss the structure of Dexamethasone, its pharmacokinetics, applications in the various fields of medicine, side effects and brief the role of Dexamethasone in the treatment of COVID-19. This article highlights the latest research developments in the use of Dexamethasone for the treatment of COVID-19. Lack of sufficient data on SARS-CoV-2 relating it to the symptoms and treatment makes it extremely significant for new age researchers to build upon the already established antiviral drugs such as Dexamethasone.
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