World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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SJIF Impact Factor: 6.842

Abstract

ANALGESIC AND ANTI-INFLAMMATORY ACTIVITIES OF METHANOLIC EXTRACT OF ACALYPHA FRUTICOSA FORSSK. IN EXPERIMENTAL ANIMALS

Sanjaya Kumar Y. R.*, Sudesh Gaidhani N., Sudheesh P.S. and Sudhakar D.

ABSTRACT

The present study was carried out to screen methanolic extract of aerial parts Acalypha fruticosa Forssk for analgesic and anti-inflammatory activities in experimental animals. Acute toxicity study was carried out in female Sprague Dawley rats and Swiss mice as per OECD guideline 423. Upon ascertaining its safety, the extract of the test drug was screened for analgesic and anti-inflammatory activities in Sprague Dawley rats and Swiss mice through various models. The test extract showed significant analgesic and anti-inflammatory activities at 250 and 500 mg per kg body weight.

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