MEFENAMIC ACID A POTENTIAL TRANSMEMBRANE SERINE PROTEASE 2 INHIBITOR IN THE TREATMENT OF COVID-19
Zeel Chaudhari, *1Pruthviraj Chaudhary, Dr. C.N. Patel, Dr. Dhrubo Jyoti Sen and Dushyant Chaudhary
ABSTRACT
COVID-19 (coronavirus disease 2019) is a Pandemic of concern, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As of now, there is no known effective pharmaceutical or other medicine available for cure or prevention of COVID-19. In this review, based on the current understanding of the disease and the structure of novel Coronavirus SARS-CoV-2, SARS-CoV and other human viruses, is has been observed that Mefenamic Acid, an anti-inflammatory medicine, of having some role as an anti-viral medicine also. It can be used along with different anti-viral drugs being tried for the treatment of COVID-19. Since it is also an anti-pyretic, its main role may be of bringing down the fever but its action as an anti-viral, as a supportive medicine can very useful. Clinical trials with this concept in mind can be started immediately at the Centres dedicated for treatment of COVID-19.
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