NOVEL BIOACTIVE NATURAL PHYTOCONSTITUENTS WITH PRONOUNCED CHEMOTHERAPEUTIC POTENTIALS
Anupama Yadav*
ABSTRACT
Cancer is the second leading cause of death in the world, with 8.8 million people dying each year. Men are more likely to develop kidney cancer, prostate cancer, colorectal cancer, stomach cancer, and liver cancer, while women are more likely to develop breast cancer, colorectal cancer, lung cancer, cervix cancer, and stomach cancer. Several medications licensed for use in cancer treatment by the US Food and Drug Administration (USFDA) are extracted from plants, like taxanes like paclitaxel and vinca alkaloids like vincristine and vinblastine. Even so, there is an urgent need to find a variety of bioactive sources in order to produce a new anti-cancer treatment to treat this chronic disease. To date, more than thirty natural products extracted from plants have been isolated and are being used in clinical trials. Novel therapeutic agents derived from bioactive sources have been shown to be clinically active against different forms of cancer cells, according to a literature review of various articles and texts. The focus of the current analysis is on novel therapeutic agents derived from plants that have the ability to treat a variety of cancers, as shown by clinical trials. The most important observations of these successful novel therapeutic agents were also presented and explored in this article.
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