World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

HISTOLOGICAL MIMICKER OF CUTANEOUS SQUAMOUS CELL CARCINOMA – MALIGNANT PROLIFERATING TRICHILEMMAL TUMOR: CASE REPORT WITH REVIEW OF LITERATURE

Dr. R. Ajitha*

ABSTRACT

Proliferating trichilemmal tumors(PTT) are benign solid-cystic neoplasms that show trichilemmal differentiation similar to that of isthmus of hair follicle. It comprises only 0.1% of skin biopsies. These tumors rarely exhibit malignant transformation. They develop from the wall of already existing pilar cyst in most cases. It is frequently seen in elderly women, more commonly on the scalp. Other locations could include face, trunk, back and forehead. These tumors are easily confused with squamous cell carcinomas. Malignant proliferating trichilemmal tumors carry significant morbidity and mortality, with possible recurrence after local excision. We present a case of a 65 year old female with rapidly growing swelling on the scalp, clinically suspected to be sebaceous cyst but later diagnosed with malignant proliferating trichilemmal tumor on histopathological examination. We also discuss the review of literature of this tumor considering the rarity of presentation.

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