Abstract

Kashish Bhardwaj, Asha Devi*, Ravinesh Mishra and Shivani Rana

ABSTRACT

The present review was aimed to find out the best natural remedies from medicinal plants like Piper betle that offer potential efficacy against inflammation. Several phytoconstituents classes such as flavonoids, triterpenoids, alkaloids, steroids, polyphenols etc. have been documented to possess interesting anti-inflammatory properties. Many of them exhibit potent bioactivities in minute concentrations against well-established biomarkers of inflammation. Natural plant metabolites extracted from medicinal herbs can act by modulating the expression of pro-inflammatory signals thus helps to manage arthritic conditions. Other than inflammation Piper betle is also reported to possess other bioactivities like antimicrobial, antibacterial, gastroprotective, wound healing, hepatoprotective, antioxidant, anti-fertility & antimotility activities etc. The review indicated that Piper betle is very useful medicinal herb to treat inflammation naturally with better safety and efficacy.