World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

FEBRILE CONVULSIONS REVEALING SYSTEMIC LUPUS ERYTHEMATOSUS IN CHILDREN OBSERVED AT THE CHU ANDRAINJATO FIANARANTSOA

Ramamonjinirinirina Tahina Prudence*, Rabemananjara Antsa, Rakotomahefa Mbola and Rabesandratana Noro

ABSTRACT

Introduction: Pediatric systemic lupus erythematosus is a rare condition. Our aim was to report a case of systemic lupus erythematosus revealed by seizures in a 9-year-old girl. Observation: We report a case of 9-year-old girl hospitalised in the paediatric service of University Teaching Hospital of Andrainjato Fianarantsoa for generalised tonic-clonic seizures. The diagnosis of SLE was based on a butterfly-shaped malar rash, oral ulceration, seizures, anaemia, and positive anti-native DNA and antinuclear antibodies. Corticosteroid therapy combined with a synthetic antimalarial drug led to an improvement in the cutaneous signs and a progressive regression of the articular signs. Conclusion: Seizure may be the mode of manifestation of SLE in children. The presence of skin and joint signs can easily guide the diagnosis.

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