Abstract

Saida Lamine*, Choukri Elm’hadi, Tarik Mahfoud, Rachid Tanz, Hassan Errihani and Mohammed Ichou

ABSTRACT

Suspicious ovarian masses always require a histological and immunohistochi-mic study to make a determination of primary or secondary status, especially in the case of bronchial cancer given the rarity of its extension to the gonads, the context of the current COVID-19 viral pandemic has disrupted the entire health system, especially in cancer, where it continues to surprise us with its positive or negative impact without being able to determine the physiopatho-logic involved in both directions. Clinical case: We report a case of a metastatic bronchial adenocarcinoma in the lymph nodes, ovaries and bones discovered following the appearance of post-vaccination cervical adenitis after the 2nd dose of anti-COVID 19 vaccine, in an asymptomatic young woman. Imaging revealed an advanced broncho-pulmonary process with multiple secondary metastasis, it is histologically a PDL1 negative pulmonary adenocarcinoma with a positive ALK rearrangement to fluorescent in situ hybridization (FISH). Conclusion: Two issues were raised by this clinical case: the primary or secondary origin of the ovarian masses, and the pathophysiological relationship between the appearance or discovery of cancer and the introduction into the body of the coronavirus or one of its component during vaccination.