Abstract

*Dr. Shishu Pal, Dr. (Prof) Jai Shankar Prasad and Dr. Santosh Kumar Vishwakarma

ABSTRACT

Yakrit roga or hepatic impairment is very common disease since ancient time and also in present scenario. There are so many causes of Liver disease but drugs are one of the most common. There are so many drugs in modern medical science and ayurveda which may induce hepatotoxicity due to side effects and excessive use of hepatotoxic drugs and herbs as- antibiotics, NSAIDS and some herbal products, but in ayurveda drug induced hepatotoxicity has resemblance to vishajanya yakrita roga and treatment of this disease is also mentioned in ayurveda and agada tantra. Gara visha is a form of slow acting artificial poison and after long time use it may cause many types of chronic disease which may effect vital organs of body as vrikka, yakrit and others. According to ayurveda and agadatantra- Nidan parivarjana, Vamana, Amashaya prakshalana, Tamra bhasm with madhu (for vomiting), Swarn makshik bhasma with madhusarkara, Nagdantiyadi ghreet, Nisotha Snuhikshira and Mainphala siddha ghreet, Amrit ghreet, Sanjivani agada and some other ayurvedic and agada drugs could be useful in treatment of gara visha janaya yakrita roga and drug induced hepatotoxicity.