World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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SJIF Impact Factor: 6.842

Abstract

EFFECTS OF WATER MELON RIND EXTRACT AGAINST POTASSIUM BROMATE INDUCED DAMAGE ON THE LIVER AND HAEMATOLOGICAL PARAMETERS OF ADULT WISTAR RATS

Chijioke U. Eze* and Ofoego Uzozie

ABSTRACT

Water melon (rind) is popular in traditional medicine and contains numerous bioactive phytochemicals. This study therefore investigated the effect of water melon rind extract against KBrO3 induced damages on the liver and haematological parameters in adult Wistar rats. Thirty adult male Wistar rats were used and randomly divided into 6 groups of 5 animals each. Group A served as control, group B received 100mg/KgBw KBrO3, group C received 1000mg/KgBw of Citrullus lanatus (CLRE), group D received 100mg/KgBw KBrO3 and 500mg/KgBw CLRE, group E received 100mg/KgBw KBrO3 and 1000mg/KgBw CLRE and group F received 100mg/KgBw KBrO3 and 1500mg/KgBw CLRE. All administrations lasted for 60 days after which they were sacrificed via cervical dislocation; blood samples and liver collected for analysis. Data were analysed using ANOVA and posthoc LCD and significant at p

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