Abstract

Ralaivaon-dratsitonta Jumael Edith Fabrice*, Andrianarijaona Mamy, Ralambomanana Dimby Andrianina, Andrianjato Tartin, Rakotondramanana Andriamahavola Dina and Randrianasolo Rivoarison

ABSTRACT

The roots of the Canarium sp (Burseraceae), an endemic species of Madagascar is used to prevent and treat cancer diseases. A phytochemical studies about this plant was effectued. The use of chromatographic technique allowed the isolation of five coumarins. They were identified as Skimmin 1, Umbelliferone 2, Scopolotin 3, Scoparone 4 and Scopolin 5. They were isolated for the first time from the roots of Canarium sp (Burseraceae). Structure elucidations of the compounds were performed by means of NMR Spectra and comparison with literature data. Two of the isolated products possess anti-cancer activity according to bibliographic studies.