World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

USE OF KETAMINE IN STATUS EPILEPTICUS, A REVIEW ARTICLE

Raghad Abdullah Almansour*

ABSTRACT

Status epilepticus (SE) is defined as any seizure that lasts more than 5 minutes, or recurrent seizures without a regain of consciousness. Refractory status epilepticus (RSE) is described by a continuous seizure despite first- and second-line agents. In the management of SE, there is a general agreement regarding the first and second lines of management. However, in RSE there is no definitive algorithm that dictates its management approach. Ketamine has shown promising efficacy and safety in the management of refractory and super-refractory status epilepticus cases. Recent studies recommended an earlier administration of KE in RSE, as it is currently being administered only after failing of conventional anaesthetics.

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