Abstract

S. Driouiche*, A. Mernissi, M. Lahlali, A. Lamine, H. Abid, A. Elmekkoui M. ELyoussfi, D. Benajah, M. ELabkari, A. Ibrahimi and N. Lahmidani

ABSTRACT

Introduction: Cirrhosis is a serious, progressive disease and constitutes a public health problem in our country being burdened with a heavy morbidity and mortality. the objective of this work is to analyze and update the epidemiological, clinical and evolutionary aspects of cirrhosis. Materials and Methods: This is a retrospective study carried out in the hepato-gastroenterology department with the aim of analyzing the characteristics of patients hospitalized for cirrhosis during the 3-year period between May 2017 and May 2019. Diagnosis of cirrhosis was posed on the basis of clinical, biological, morphological and endoscopic arguments. Results: Over a period of 3 years, 124 cases of patients with cirrhosis were hospitalized in the hepato-gastroenterology department. The average age was 54.24 (19 - 91 years) with male predominance, a sex ratio of 1.19. In the history, viral hepatitis was known in 9 patients (9.6%). The causes of hospitalizations were gastrointestinal bleeding, hepatic encephalopathy, infection of ascites fluid respectively in 40%, 17% and 5.6%. Viral infections B and C rank first among etiologies in 35 cases (29%), followed by portal thrombosis in 17 cases (11.29%) and alcohol in 7 cases (5.6%). Distribution of the child: A in 50 cases (40%), B in 25 cases (20%), C in 8 cases (6%). The main complications that occurred during the course were: digestive hemorrhage in 50 cases ( 40.3%), hepatic encephalopathy in 22 cases (17%), death in 12 cases (9.6%), renal failure in 8 cases (6%), infection of ascites fluid in 7 cases (5.6%) ) and hepatocellular carcinoma in 2 cases (1.6%). Conclusion: viral causes are still the main cause of cirrhosis in our population with heavy morbidity and mortality mainly linked to digestive bleeding and complications of ascites. Key words: hepatic cirrhosis, various etiologies, viral hepatitis, heavy morbidity and mortality. Introduction: Cirrhosis is a serious and progressive disease and constitutes a public health problem in our country, with a high morbidity and mortality rate. The aim of this study is to analyse and update the epidemiological, clinical and evolutionary aspects of cirrhosis. Materials and Methods: This is a retrospective study carried out in the department of hepato gastroenterology with the aim of analyzing the characteristics of patients hospitalized for cirrhosis during the 3-year period between May 2017 and May 2019. The diagnosis of cirrhosis was made on the basis of clinical, biological, morphological and endoscopic arguments. Results: Over a period of 3 years 124 cases of patients with cirrhosis were hospitalized in the hepato gastroenterology department. The average age was 54.24 (19 - 91 years) with male predominance, a sex ratio of 1.19. 9 patients (9.6%) were known to have viral hepatitis. The causes of hospitalization were digestive hemorrhage, hepatic encephalopathy and ascites infection in 40%, 17% and 5.6% respectively. Viral infections B and C were the most common etiologies in 35 cases (29%), followed by portal thrombosis in 17 cases (11.29%) and alcohol in 7 cases (5.6%). Distribution of the child: A in 50cas (40%), B in 25 cases (20%),C in 8 cases (6%).The main complications occurred during the course of the evolution were: digestive hemorrhage in 50 cases (40. The main complications that occurred during the course of the disease were: digestive hemorrhage in 50 cases (40.3%), hepatic encephalopathy in 22 cases (17%), death in 12 cases (9.6%), renal failure in 8 cases (6%), infection of ascites fluid in 7 cases (5.6%) and hepatocellular carcinoma in 2 cases (1.6%). Conclusion: Viral causes are still the main cause of cirrhosis in our population with a high morbimortality related mainly to digestive hemorrhage and complications of ascites.