World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
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ICV : 78.6

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Abstract

A CLINICAL AND COMPARATIVE STUDY OF MANADYA GUDIKA & SHOBHANJANADI KWATH IN THE MANAGEMENT OF YAKRITPLEEHA VIKAR

*Dr. Janmajay Sidar and Dr. Pramod Kumar Baghel

ABSTRACT

The liver is the largest organ and gland in the human body and it is responsible for both metabolism and detoxification. Acharya Charak and Sushruta mention that the Yakrit (liver) and Pleeha (spleen) are the two organs that originated from Shonita (blood) in Ayurveda. Both Yakrit (liver) and Pleeha (spleen) are roots of the Shonitvaha Srotsa. According to Ayurveda Ranjaka pitta, which is found in the liver and spleen, is responsible for Rakta dhatu's (blood) production. As a result, hepatomegaly and splenomegaly should be treated with Rakt Dhatu in mind. To treat hepatomegaly and splenomegaly, 15 of the herbal contents in Manadya Gudika and 5 of the herbal contents in Shobhanjanadi Kwath are used. Giloya, Pippali Chitrak and Shobhanjan, are the main hepatoprotective, carminative, and blood purification drugs used in this Shastriya Aushadh Yog. An evidence-based medicine, that can benefit other Vaidyas and the medical community for the treatment of hepatomegaly and splenomegaly. Aim: A Clinical and Comparative Study of Manadya Gudika and Shobhanjanadi Kwath in the Management of Yakritpleeha Vikar. Design: This study was conducted as a prospective, open-level clinical, interventional, & comparative trial with before and after treatment with the administration of Manadya Gudika (1 gm per day) and Shobhanjanadi Kwath (40 ml per day) for a period of 90 days with a follow up of 15 days. Method: This is a study with a sample size of 22 patients in each group (Group A and B). A total of 44 patients with hepatomegaly and splenomegaly were chosen from the O.P.D. of Shri Khudadad Dunga ji, Govt. Ayurved College Hospital Raipur (C.G.) between the ages of 18 and 60. Results: The clinical study showed highly significant results in relieving the clinical symptoms of Yakrit vikar (Hepatomegaly) and Pleeha vikar (Splenomegaly).

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