Abstract

Sanskar Shrivastava* and Varsha Kashaw

ABSTRACT

Recently, to study drugs with different physicochemical properties new methods are being studied so as to achieve analytical methods with a high sensitivity and selectivity along with reduction in the time for analysis. This is very significant in the analytical studies involved in the clinical studies. This is especially true when analytical procedures are applied to clinical purposes. Additionally, multi-drug therapy are frequently utilised to treat a variety of disorders so as to sidestep the major side effects involved with usage of high dosage of single medicine. Thus in recent times this has led to elevation in the requirement of techniques enabling rapid analysis of mixed constituents. New tools and techniques are being studied in order accomplish these needs. Due to the intricacy of the matrix the sample preparation and subsequent processing might be time consuming. Not only this but numerous issues arise in matrices, compounds and components while investigating drug association profiles of physical and chemical nature. This review covers methodologies used for the simultaneous estimation of drugs that in the quantitative analysis provides us accuracy and sensitivity.