A COMPREHENSIVE REVIEW ON CONTROLLED DRUG DELIVERY SYSTEMS: FUTURE DIRECTIONS
Mohsin Khan* and Dr. Yuvraj singh Dangi
ABSTRACT
The drug delivery system allows for the release of the active pharmaceutical ingredient to achieve the desired therapeutic outcome. Conventional drug delivery methods (tablets, capsules, syrups, ointments, etc.) do not achieve sustained release due to their poor bioavailability and variable plasma drug levels. Without a trustworthy delivery method, the entire therapeutic procedure may be unsuccessful. The medication must also be given at the intended location and at a precise controlled pace in order to achieve maximum efficacy and safety. By creating controlled medication delivery systems, the problems with conventional drug administration are solved. Systems for controlled drug delivery have significantly changed during the past 20 years, moving from large and nanoscale to intelligent focussed delivery. With an emphasis on the pharmacokinetics of the drug, the first section of this paper provides a basic overview of drug delivery techniques. The limitations of conventional drug delivery techniques are also discussed. Additionally, controlled drug delivery systems are thoroughly discussed, along with design elements, groups, and examples. Along with recent significant findings, the application of stimuli-responsive and intelligent biomaterials for targeted and smart medicine distribution is also presented. In the paper's conclusion, the challenges and potential opportunities for regulated medication distribution are examined.
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