World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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SJIF Impact Factor: 6.842

Abstract

BILIARY LITHIASIS IN CIRRHOTIC PATIENTS: PREVALENCE AND RISK FACTORS

I. Ouchicha*, H. Cherkaoui, A. Lamine, M. Lahlali, N. Lahmidani, A. El Mekkaoui, M. Elyousfi, DA. Benajah, A. Ibrahimi, M. Elabkari and H. Abid

ABSTRACT

Gallstones occur in about one-third of patients with cirrhosis, the pathophysiology is complex and multifactorial and could be due to decreased secretion of bile acids and phospholipids into the bile and hypomotility of the gallbladder. Our work aims to study the prevalence of biliary lithiasis in cirrhotic patients and to identify risk factors for cholelithiasis in cirrhotics. In our retrospective and analytical study, gallstones were found more frequently in cirrhotic patients (45.45%, P=1.046.10^(-8), RR=2.17) than in non-cirrhotic patients (10%). The prevalence of gallstones in decompensated cirrhotic patients was higher (P=1.272.10^(-5)) than in compensated cirrhotic patients.

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