EVALUATION OF HAEMORHEOLOGICAL PARAMETERS AND ATHEROGENIC INDEX OF PLASMA AND CASTELLI RISK INDICES OF APPARENTLY HEALTHY ADULTS IN PORT HARCOURT, NIGERIA
Ebirien-Agana S. Bartimaeus* and Stella U Ken-Ezihuo
ABSTRACT
Aims: Evaluation of lipoprotein profile, atherogenic ratios and haemorheological parameters as indicators and significant adjuncts for predicting atherosclerosis in an apparently healthy population was investigated. Methodology: A total of 300 subjects comprising 169 (56.3%) males and 131 (43.7%) females within the age range of 18-45 were recruited into the study. Haemorheological parameters such as haemoglobin, haematocrit, erythrocyte sedimentation rate, platelets, fibrinogen, whole blood viscosity and plasma viscosity were determined using standard methodologies. Fasting lipid profile parameters were assessed using standard procedures. Results: Results of the lipoprotein determinations were used to calculate the atherogenic indices namely Atherogenic Index of Plasma, and Castelli Risk Index I and II. Analysis of variance and student t-test were used to compare the means of the parameters. ANOVA analysis of the means of the haemorheological parameters showed no significant difference (p>0.05) in the means of the haemorheological parameters between the age classes except for fibrinogen (p
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