World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

A COMPARATIVE CLINICAL STUDY TO EVALUATE THE EFFECT OF “NISHALAUHA WITH FERROUS SULPHATE” IN THE MANAGAMENT OF PANDU W.S.R. TO IRON DEFICIENCY ANAEMIA

Dr. Ajay Kumar* and Dr. Anuradha Lalotra

ABSTRACT

Introduction: Anaemia is the most prevalent disorder in the world. Anaemia refers to a state in which the level of haemoglobin in the blood is below the normal range for corresponding age and sex. Pandu Roga as disease may very well compare with Anaemia. In our classical texts, the description of Pandu is available in three forms; i.e. Pandu as a disease, Pandu as a complication and Pandu as a sign of certain diseases. Aim: To evaluate and compare the effect of Nishalauha and Ferrous Sulphate on Pandu (IDA) Material and Methods: The study was conducted in 40 clinically diagnosed patients of anaemia. There were two trial groups with 20 Patients in each trial group. Group 1- In this group each subject was given 500 mg tab of Nishalauha once daily. Group II- In this group each subject was given 200 mg tab of Ferrous Sulphate once daily. Total duration of the trial was 30 days. Follow up was done after every 15 days of commencement of therapy. Among 40 registered patients, 36 patients had completed the treatment and 4 patients discontinued the treatment. “Paired t-test” was carried out for various objective parameters within the group and “unpaired t-test” was carried out between the groups. Result: At the end of study, drug has shown beneficial effect in the patients of anaemia. The trial drug Nishalauha is effective to improve clinical features and hematological parameters significantly. The medicine is effective to increase the hemoglobin level 1.58 g/dL (9.79- 11.37g/dL, P < 0.001) in 30 days. No adverse effect of the trial drug was observed during the study. Conclusion: The results suggest that Nishalauha is significantly effective in the management of IDA.

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