3-D TECHNIQUES IN PHARMACY: A STATE-OF-THE-ART REVIEW
Ajay Singh*, Ankit Sharma, Kashish Bhardwaj, Dhiraj Kumar, Abhishek Kumar and Riya Thakur
ABSTRACT
3-Dimensional techniques for drug dosage design and development have potential applications in pharmaceutical industries and patient co-centric problems. It is a forecast for the way of manufacturing and reshape the way of designing the medicines. The 3-Dimensional techniques give us innovative solutions to prepare and develop drug dosage design, especially in oral dosage form, the utilization of these techniques facilitates the fast disintegration time, low volumes with higher accuracy, preparation of these dosage form layer by layer, spatial arrangement produces highly porous yet fast oral dispersible tablets, wide range of taste masking capabilities cause ease of swallowing. These techniques facilitated the drug designing by methods like Stereo lithography (SLA), Selective Laser Sintering (SLS), Direct Metal Laser Sintering (DMLS) and Fused Deposition Modeling (FDM). Development of drug dosage designing, patient centric drug problems (such as can be resolved by the help of 3- Dimensional techniques, the oral dosage form prepared by these 3-dimensional technique are Implant Tablets, ODT (oral disintegration tablets), bilayer tablets, capsules and tablets. Here we will accentuate the challenges, advantages, disadvantages, types of medicines, pharmaceutical application (dosage form design and development), comparison (between the 3-dimensional techniques and other oral dosage form manufacturing techniques) and make a conclusion about the 3-dimensional techniques.
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