Abstract

Ouail Benzerouale*, Fatima-Zahra Kahouadji, Sihame Lkhoyaali, Sarah Naciri, Saber Boutayeb, IbrahimEl Ghissassi, Hind M’rabti and Hassan Errihani

ABSTRACT

Synovialosarcoma is a rare mesenchymal tumor with a poor prognosis. It accounts for 8% of soft tissue sarcomas. Its diagnosis is facilitated by immunohistochemical methods, but above all by molecular biology. It usually develops in the limbs, but its pulmonary localization remains exceptional. We report a clinical case of synovialosarcoma of the lung in a 54-year-old woman, discovered at a localized stage. This extremely rare tumor presents a particular immunohistochemical phenotype, which strongly contributes to the diagnosis. Cytogenetic studies confirmed the diagnosis, showing the presence of the characteristic specific translocation t (X; 18). This article highlights the diagnostic, therapeutic and prognostic features of this rare tumour, which is often overlooked by clinicians.