Abstract

*Dr. Rajesh Kumar Urmale and Dr. Arun Kumar Das

ABSTRACT

In present era Ayurvedic pharmaceutical industry spreading worldwide. Demand of Ayurvedic drugs is increasing day by day. The Ayurvedic drugs which are useful in the diseases related with joints, skin, hair, heart and digestion are more in demand. Today’s change in lifestyle, resistance to new molecule of modern drugs and pandemic situation are important causes for the creating demand of the Alternate system of medicine.[1] Life style diseases like diabetes, obesity, cardiac disorders etc are becoming very common now a days. Obesity and atherosclerosis are mainly caused by disturbance in lipid metabolism. This can be corelate with Medo dhatu dushti as per ayurvedic pathogenesis.[2] Dashang Guggul is one of the very importance polyherbal formulation mentioned in the classical treaties of Ayurveda.[3] This formulation is commonly used in medo dhatu dushti janya vikara. Guggul is chief component of this formulation. Guggul (Commiphora wightii) is a oleo-gum or the resin part of guggul plant obtained from its stem. Nevertheless, the usage of this without subjecting to shodhana (detoxification process) may lead to certain side effects like gastric irritation and gastric distress.[4] So the Guggul shodhana plays an important role in pharmaceutical preparation of any Guggul Kalpana. In addition to it, shodhana of guggul in different media will bring specific properties to Guggul.[5] In present study Dashang Guggul is prepared in two batches. Guggul used in both batches is purified in two different media e.g. Triphala Kashaya and Dashmool kashay. After pharmaceutical preparation of both Guggul, analytical study is carried out for comparative analysis.