Abstract

Bolinjkar A. N., Singh Ayushi* and Talpade M. B.

ABSTRACT

The environment encompasses a diverse array of deleterious compounds which is crucial to consider the potential on humans to elicit toxicological responses in other organisms. Notable examples include caffeine, capsaicin, and nicotine which are consumed all around the world and are part of our everyday lives. This study aims to explore the toxicity and teratogenicity of these toxins on 72-hour-old chick embryos. Three concentrations (5%, 10%, and 100%) of the isolated toxins were investigated. The findings indicate a significant impairment in the developmental capacity of treated embryos. Caffeine and capsaicin resulted in reduced sizes and morphological alterations in the embryos. Nicotine exhibited detrimental effects on eggs, leading to embryo demise. Capsaicin appeared to impact both neural and internal organ development. A substantial hindrance in growth is characterized by caffeine's effects. In conclusion, caffeine exposure can affect the closure of neural folds, Capsaicin can lead to retarded growth, and nicotine toxicity can affect brain development. However, the exact mechanism of these effects requires further investigation.