World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

EXPLORING THE RELATIONS & VARIATIONS OF RISK FACTORS, SYMPTOMS AND DIAGNOSTIC TOOLS IN ACUTE CORONARY SYNDROME

Suman Sasmal*, Kumar Sanu, R. S. N. Vinay, Aritra Pal, Asish Bhanja, BashongdorMarwein, P. Ratna Kumari and B. Durga Pavan Kumar

ABSTRACT

Acute coronary syndrome (ACS) refers to a group of conditions that include ST-elevation myocardial infarction (STEMI), non-ST-elevation myocardial infarction (NSTEMI) and unstable angina (UA). The Genome Database study estimated that there were 1.2 million incidental ACS patient in year 2017. Data for 2020, from USA estimate a total of 3.5 million deaths with approximately 7% caused by MI, assuming a 30% of fatality rate. This is a type of coronary syndrome, which is responsible for 1/3rd of total death in people older than 35. Some forms of (Chronic heart disease) CHD can be a symptomatic, but ACS is always symptomatic, our study aims to give a detailed information on the analysis of symptoms and diagnostic tests and risk factors in acute coronary syndrome affected inpatients. It was a prospective observational study that was conducted in Trust Multispecialty Hospital, Kakinada. 223 patients (subject) who got admitted in hospital in the duration Nov’22 to Nov’23. Mainly SOB, cough, palpitation where the major symptoms are selected. Type-II DM, hypertension, overweight were the major risk factors. ECG & 2D-ECHO were mostly used to diagnosis ACS. Mainly the variations of symptoms and estimate the risk factors related to ACS and their contribution in the disease would be monitored. There are important dissimilarities in clinical presentation, aggregation of comorbidities, cardiovascular risk factors among men and women with acute coronary syndrome (ACS). Compared with men, despite the well-known older age and more pronounced frailty, they more often experience myocardial infarction in the absence of obstructive coronary arteries (MINOCA), which makes diagnosis and treatment of ACS among women more challenging compared with men. Women and men do both benefit from guideline-recommended treatment, although, compared with men, women with ACS have a higher adjusted risk of early death, which equalises between both sexes within the first year.

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