GORLIN-GOLTZ SYNDROME: ABOUT A CASE
Dr. Salma Regeraji* and Malik Boulaades (PF)
ABSTRACT
zGorlin-Goltz syndrome is a hereditary condition, with autosomal dominant transmission, due to a mutation in the PTCH gene with chromosomal location 9q 22.3-q31. It is a rare syndrome characterized by a spectrum of developmental abnormalities and a predisposition to different cancers. The complexity of clinical signs has led to the establishment of specific criteria to facilitate diagnosis. Therapeutic management is symptomatic, with rigorous oncological monitoring. We report a new observation of Gorlin-Goltz syndrome in a 45-year-old man and, through a literature review, we discuss the main characteristics of this rare condition.
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