Abstract

Uriti Sri Venkatesh, Vilas Nilkanthrao Deshmukh, Amit Pandey, Kanishka Tara Rana and Anil Kumar*

ABSTRACT

The field of cancer treatment is plagued by serious obstacles, which led to the study of new therapeutic strategies. Zinc oxide nanoparticles (ZnO NPs) are a potential cancer treatment agent, which has received considerable attention for its unique properties and potential cancer resistance properties. The following is a comprehensive analysis of current research on the anti-tumor properties of ZnO NPs. It starts with a discussion of the characterization techniques and synthesis methods used in the production and examination of ZnO NPs. After that, we investigate the mechanisms that are responsible for their anti-tumor properties, including their ability to produce reactive oxygen species (ROSs) and stimulate apoptosis in cancerous cells. In addition, in vitro and in vivo studies are reviewed to evaluate the effectiveness of ZnONP against a variety of cancers. Despite their promising nature, barriers such as bioavailability and toxicity must be overcome before clinical implementation. The review concludes with a discussion on the potential applications and future prospects of ZnO NP in combination therapy and targeted drug delivery systems. The aim of this study is to provide a detailed analysis of current research on ZnO NP in cancer therapy and to provide guidance for future research in this blessed field.