Abstract

Oyubu Lenvison Obaro, Adomi Patience O., Jewo Augustina Oghenevwaerhe and *Enwa Felix Oghenemaro

ABSTRACT

This study was carried out to determine the incidence of colistin resistance in hospitalized patients. Ten samples of high vaginal swap and twenty samples of urine were collected from out patients ofgeneral hospital, Agbor, Delta State. The organisms isolated from the samples included the following; Enterococcus faecalis, Staphylococcus aureus, Bacillus Subtillis, Staphylcoccus epidermidis, Bacillus cereus, Streptococcuspyogene, Pseudomonas aeruginosa, Eschericha coli, Enterobacteraerogeneand Neisseria gonorrhoeae. Sensitivity test was carried out on the isolates obtained after morphological and biochemical tests had been carried out. The percentage prevalence of test isolate from urine sample showed that out of a total of 12 isolates, Staphylococcus sp had the highest percentage prevalence of 58.3% while Entrococcusfaecalis had the least percentage prevalence of 8.3% whereas the percentage prevalence of the isolates from high vaginal swap showed that Staphylococcus sp. had the highest percentage prevalence of 35% while Pseudomonas aeruginosa, Neisseria gonorrhea and Enterobateraerogene had the least percentage prevalence of 5% each. A high detection rate of colistin resistance among isolates was oserved in this study. All gram negative isolate were resistant to colistin. The increasing trend in antibiotic resistance especially to last resort drug as colistin continues to threaten global health and this is worrisome.