FORMULATION AND EVALUATION OF HERBAL OINTMENT BY USING DYEROPHYTUM INDICUM EXTRACT
Ajay S. Dongarwar*, Shubham A. Parihar, Vaibhav N. Nagpure, Tushar K. Bhonde, Satyam V. Deshmukh, Vansh A. Khandelwal
ABSTRACT
Dyerophytum indicum belong to the family Phumbaginaceae is a small herb well known for its medicinal properties and widely used as worldwide. It possoses wide range of phytochemicals showing various pharmacological activities. Dyerophytum indicum is an important plant used in the treatment of arthritis, tooth ache, leprosy, anaemia, and stimulate the power of digestion and metabolism. Method: The extract was obtained by the maceration method with 90% ethanol. simple ointment IP was use as ointment base for dispersion of the plant extract parameter investigated includes spreadability, pH and viscosity of extract. Result: Dry leave of part of plant powder and extract by maceration technique of extraction with ethanol. The pH of ointment was 6.06 ± 6.10 and the spreadability was 45 ± 48mm slightly washable and non irritant viscous in natue, insoluble in water, soluble in ether and chloroform, no pink colour from the rancidity test are passed and loss on drying is passed. Conclusion: Dyerophytum indicum ethanol extract has a good therapeutic value for combating tropical infection disease. The Dyerophytum indicum ointment is used as a potential agent for treatment of skin infection.
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