World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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SJIF Impact Factor: 6.842

Abstract

A REVIEW ON ANALYTICAL METHODS FOR ESTIMATION OF ABIRATERONE ACETATE

Pushpa Latha E*, Syeda Bushra Yunus, Navya Sree O, Juveriya Naz, Anusha M, Mani Sagar G,
Sameul Shine S.

ABSTRACT

Abiraterone acetate is a derivative of steroidal progesterone that offers clinical benefit to patients with hormone refractory prostate cancer. Few analytical methods used for the estimation of Abiraterone has been reviewed in this paper. These include High performance liquid chromatography, Liguid Chromatography – Mass spectroscopy, Spectrofluorimetry to determine the amount of Abiraterone acetate in bulk drugs, pharmaceutical formulations and biological fluids. Stability indicating method for Abiraterone acetate is also described. These analytical methods can be used for qualitative and quantitative estimation of Abiraterone acetate, its related impurities or degradants in bulk, formulation and biological fluids.

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