Abstract

Gauri Vitthal Chavale*, Pratiksha Raman Kabde, Shrimangale Ayodhya Ramesh, Harshdeep Sunil Sapkal

ABSTRACT

Because of their distinct physiological and developmental traits, preterm newborns with Acute Respiratory Distress Syndrome (ARDS) present considerable hurdles. The epidemiology, pathophysiology, clinical presentation, diagnosis, therapy approaches, and consequences of ARDS, particularly in preterm newborns, are summarized in this review. Important subjects include the unique processes of lung damage, difficulties in obtaining an early diagnosis, breathing systems that are improved, and novel treatments such stem cell-based methods and bioengineered surfactants. Future directions include the use of precision medicine, developments in non-invasive monitoring and imaging methods, and the necessity of multicenter collaborative research to improve knowledge and treatment of this life-threatening illness. This review attempts to direct future activities for improving outcomes and lowering morbidity associated with ARDS in preterm children by addressing gaps in existing research and clinical practice.