World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

World Journal of Pharmaceutical and Medical Research (WJPMR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Indian Science Publications , Cosmos Impact Factor , Research Bible, Fuchu, Tokyo. JAPAN , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , International Innovative Journal Impact Factor (IIJIF) , Scientific Journal Impact Factor (SJIF) , Global Impact Factor (In Process) , Digital Online Identifier-Database System (DOI-DS) , Science Library Index, Dubai, United Arab Emirates , Eurasian Scientific Journal Index (ESJI) , International Scientific Indexing, (ISI) UAE , IFSIJ Measure of Journal Quality , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

Abstract

CLINICAL EFFICACY OF NISHA LAUHA VATI AFTER VIRECHANA KARMA IN PANDU ROGA W.S.R TO IRON DEFICIENCY ANEMIA

Dr. Vishal Saxena*, Dr. Sanjay Kumar Tripathi, Dr. Neetu Lata Bhatt

ABSTRACT

Anemia is a global public health problem affecting both developing and developed countries with major consequences for human health as well as social and economic development. It occurs at all stages of the life cycle, but is more prevalent in pregnant women and young children. According to WHO Global Database on Anemia- “Worldwide Prevalence of Anemia 1993-2005, it affects 1.62 billion people which correspond to 24.8% of the population. Globally, iron deficiency ranks number 9 among 26 risk factors included in the GBD 2000, and accounts for 841,000 deaths and 35,057,000 disability-adjusted life years lost. Study design: The study was “Single blind study” conducted on 60 patients of Pandu. All selected patients were randomly assigned to three treatment groups, Group A (Nisha Lauha Vati), Group B (Nisha Lauha Vati after Virechana Karma) & Group C (Iron tablet). Total duration of study was 60 days along with a follow up period of 15 days. Assessment was done on the basis of subjective and objective parameters. Results: All the interventions were found to be significantly effective, but Group B showed maximum improvement. The overall effect of Group B was better than Group A & Group C. In Group B, excellent improvement was seen in 16.6% of patients and 66.6% patients shows marked improvement. Discussion: The ingredients of In Nisha Lauha Vati iron is present. Katuki is a Pitta Virechaka having Shodhan property. Triphala in this drug is Rasayan & also have the property of Shodhan Karma. Haridra and Daruharidra present in is Nisha Lauha Vati Tikta Katu and Tikta-kashaya Rasa Pradhan respectively and also Ushna Virya having good effect on liver function as well as Amapachak. Because of all these drug present in Nisha Lauha Vati, we can think that there is increased absorption of iron in the body result in rapid formation of hemoglobin. In “NISHA LAUHA VATI” majority of drugs are having Tridoshahara property, so it becomes helpful in treating Tridoshaj Vyadhi PANDU. Majority of drugs are having Deepana, Pachana property. So drug increases the Jatharagni and Dhatvagni up to normal level and the drug diminishes Mandagni and breaks the pathogenesis of PANDU ROG. Maximum no of Dravyas possess Laghu, Ruksha Guna and Tikta Kashaya Ras so the drug also posses Srotoshudhikara property as a result it is able to clarify the Srotas. Conclusions (1) Pandu roga and Iron Deficiency Anemia both are nearly same entities.(2) Nisha lauha vati , when given after Virechana Karma is quite effective in managing the patients of Pandu roga (Iron Deficiency Anemia). As, Nishalauh vati due to its contents did Agni deepana, AmaPachana and Vataanulomanam thus breaking the pathogenesis of Pandu Roga. Nisha lauh vati is very effective after virechana karma in controlling the aggravated Pitta pradhan tridoshajavyadhi (Panduroga). So, it can be concluded that the Ayurvedic management provide better alternative to Allopathic drugs in treating Panduroga (I DA)without any side-effects as seen Constipation, Nausea etc.(3) Result of group II NISHA LAUHA VATI AFTER VIRECHANA KARMA was encouraging in terms of providing relief on subjective and objective parameters of pandu roga as compared to group I (NISHA LAUHA VATI)& group III (Tab.Iron). Thus it can be concluded that NISHA LAUHA VATI AFTER VIRECHANA KARMA is more effective in management of panduroga .in comparison to NISHA LAUHA VATI & Tab.Iron alone.

[Full Text Article]    [Download Certificate]

Powered By WJPMR | All Right Reserved

WJPMR