VARIOUS MECHANISMS OF DRUG RESISTANCE IN MYCOBACTERIUM TUBERCULOSIS – A COMPREHENSIVE REVIEW
Priyanka Tanwar*, Mamta Naagar and Manish Kumar Maity
ABSTRACT
Globally, tuberculosis (TB) is a severe public health issue. The presence of multidrug resistant (MDR) strains of Mycobacterium tuberculosis, the disease's causative agent, exacerbates its condition. Even more severe cases of medication resistance have been documented in recent years. Improved methods for quickly detecting drug resistance in M. tuberculosis and the exploration of novel targets for therapeutic activity and development will result from a deeper understanding of the molecular processes behind drug resistance in this pathogen. The methods of action of anti-tuberculosis medications and the molecular causes of treatment resistance in M. tuberculosis are covered in this study.
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