World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

MRI NEGATIVE CENTRAL PONTINE MYELINOSIS

Dr. Mudasir Ahmad Dar*, Dr. Omar Farooq, Dr. Sobia, Dr. Javed Chacho and Dr. Irfan Shah

ABSTRACT

80 year old male with underlying hypertension with recent history of chlorthalidone induced symptomatic hyponatremia (Na-103) was managed in peripheral hospital with 3% saline presented to our emergency department with sudden onset altered sensorium. On physical examination HR was 90 b/m and BP of 120/80. Baseline investigations were normal except serum sodium of 130 mmol/l but was rigid, mute and not moving any limb(Akinetic rigid state). Central pontine myelinosis was suspected and MRI brain(fig-1) was done which was normal. Patient was managed as case of central pontine myelinosis and repeat MRI brain(fig-2) was done after 2 weeks which was suggestive of pontine myelinosis.

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