Abstract

Senthil Prabhu R.*, Suresh M., Balaji S., Govindhan A. and Sathiyarasu S.

ABSTRACT

Microemulsions are transparent, thermodynamically stable colloidal systems. Over the recent years, they have been increasingly investigated due to their potential as skin delivery vehicles for a wide range of drug molecules. It can able to incorporate hydrophobic drugs, butdue to low viscosity of microemulsion it is unable to easily spread on the skin, hard to handle. On the other hand, gels provide sufficient viscosity for application of topical use. Clinical evidence indicates that topical gel is a safe and most effective treatment option for use in the management of skin related disease and used for local actions. But gels have limitation of inability to incorporate hydrophobic drugs. Low water soluble/water insoluble drug can be delivered through transdermal route by fabricating the microemulsion into gel system. This article discuses about formulation and characterization of microemulsion based gel and recent research work that formulate drug in the microemulsion based gel system.