SEPARATION IDENTIFICATION OF BIOACTIVE COMPOUNDS AND PREPARATION OF A HERBAL TOPICAL FORMULATION OF CURCUMIN
Tejas N. Zuge*, Nikhil D. Zuge, Ganesh V. Mohite, Vitthal S. Barkade and Suraj M. Gholap
ABSTRACT
Curcumin is one of the main active ingredients of roots or rhizomes of curcuma longa. The roots are found to be medicinally valuable.[1] The molecules has many potent therapeutic activities like antioxidant, ant-inflammatory, ant0icancer, antibacterial, wound healing, anti-viral, hepatoprotective, neuroprotective. It may help in the treatment of inflammation and muscle pain brought on by exercise, improving recuperation and performance in athletes.[2] Additionally, those without medical diagnoses may benefit from a very low dosage of the complex.[3] Its anti-inflammatory and antioxidant properties are responsible for the majority of these advantages.[5] Curcumin's low bioavailability, which seems to be mostly caused by poor absorption, fast metabolism, and rapid elimination, prevents it from providing the health advantages when consumed alone.[6] Bioavailability can be increased by a number of factors.
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