World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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SJIF Impact Factor: 6.842

Abstract

PHYTOCHEMICAL STUDIES AND ANTIOXIDANT ACTIVITY OF WITHANIA SOMNIFERA PLANT ROOT PROTEINS

Dr. Dinesha Ramadas*, Dr. Ravishankar M., Dr. Shwetha S. and Dr. Chikkanna D.

ABSTRACT

The phytochemical analysis and antioxidant activity of Withania somnifera root proteins was evaluated. The quantitative phytochemical study was done for the dialyzed ammonium suphate precipitated proteins. Free radical scavenging activity was evaluated using 1,1-Diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay and nitric oxide scavenging assay. The study reveals that, the Withania somnifera root proteins showed potent antioxidant activity in scavenging DPPH and Nitric oxide radicals in comparison with standard antioxidants like Ascorbic acid and BHA at a lower dose of 12 and 10?g respectively. The dialyzed protein precipitate contains more proteins and negligible amount of other phytochemicals.

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