Abstract

Yash Srivastav*, Anjani Mishra and Nutan Shrivastava

ABSTRACT

Clostridium tetani is the bacterium that causes tetanus, also referred to as lockjaw, which is characterized by muscle spasms. The most prevalent kind causes the jaw to tremble first, then the rest of the body. In 1884, tetanus was first created in animals by injecting them with pus from a fatal human tetanus case, even though clinical descriptions of the disease date back to documents from the 5th century B.C. Painful, uncontrollable jaw spasms are frequently the initial symptoms of widespread tetanus. Ten days on average after the pathogen enters your body, tetanus symptoms appear. However, they may begin three days after infection or three weeks or longer later. Additional early signs of tetanus include: Additional signs of tetanus. Tetanus toxoid (TT), another name for the tetanus vaccine, is a toxoid vaccination that is used to prevent tetanus. Crystal Bae; Bourget, Daniele. Current Date of Update: May 31, 2023. Lockjaw, commonly known as trismus, and muscle spasms are symptoms of tetanus. Clostridium tetani produces toxins that are in charge of the distinctive appearance. During the 1990s, tetanus infection rates in many Asian and African nations exceeded 5 cases per 100,000 years. Several nations have tetanus infection rates of more than 20 per 100,000 inhabitants, including Somalia, India, Pakistan, and Chad. However, by 2019, many countries had seen a decrease in infection rates, and only a few nations had annual tetanus infection rates of more than 5 per 100,000 people. In this article, we assess tetanus's present state, possible therapies, and underlying causes.