Abstract

Akshay Acharya N*, Varsha M, Abeda Abed Moqbel Garman, Dr. Umesh M, Dr. Deekshith A, Dr. Raghuveer M N, Dr. Dinesh H N, Dr. Charan C S and Dr. Hanumanthachar Joshi K

ABSTRACT

Background information: Ceftriaxone and metronidazole are the antibiotic medications used for the management of bacterial infections and in the treatment of diabetic foot infection. Objectives: To determine the efficacy of the ceftriaxone monotherapy and the combination therapy of ceftriaxone and metronidazole in patients with diabetic foot infection. To identify the microbes causing infection in diabetic foot patients. Methods: A prospective observational study. Was carried out in general surgery department, Krishna Rajendra hospital, Mysuru for a period of 6 months. The study include participants with diabetic foot infection and the patients were divided based on the severity by using Wagner classification of diabetic foot and treatment was given accordingly and their efficacy has been analyzed. Result: 120 people are included in our study population, of which 35.8%(n=43) were male and 64.2% (n=77) were female patients having diabetic foot infection. The ceftriaxone and metronidazole showed 83.30% (n=50) of effectiveness, 15%(n=9) of moderately effectiveness and 1.70%(n=1) of not effectiveness. The ceftriaxone showed 28.30%(n=17) of effectiveness, 33.30%(n=20) of moderately effectiveness and 38.31%(n=23) of not effectiveness. Over all the combination therapy of ceftriaxone and metronidazole was more effective in diabetic foot infection. Conclusion: The study evaluated the effectiveness of ceftriaxone and metronidazole with ceftriaxone for treating diabetic foot infection. Results showed the ceftriaxone was more effective in mild cases, while combination therapy was more effective in moderate cases. The study emphasizes the importance of early diagnosis, careful antibiotic selection and patient education for better prognosis and quality of life.