World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
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Abstract

AN OPEN LABEL SINGLE ARM CLINICAL STUDY TO EVALUATE THE EFFICACY OF DARVYADI CHURNA PRAYOGA IN THE MANAGEMENT OF PRAMEHA (TYPE 2 DIABETES MELLITUS)

Dr. Anjan Saloi*, Dr. Bhagyesha K. and Dr. Anush N.

ABSTRACT

Background: The prevalence of diabetes has surged dramatically since the early 2000s, primarily due to rising obesity rates and sedentary lifestyles. According to the latest 2021 data from the IDF Diabetes Atlas (10th edition), approximately 537 million adults are currently affected by diabetes, with projections estimating this number will increase to 643 million by 2030 and 783 million by 2045. India is expected to have around 109 million individuals with diabetes mellitus (DM) by 2035, with type 2 diabetes (DM2) constituting nearly 90% of all cases. Thus, Darvyadi Churna with warm water for 30 days was selected for the study. Objective: To study the efficacy of Darvyadi Churna in the management of Prameha (Type 2 DM) Methodology: Among the 35 registered subjects 30 completed the course of treatment. They were administered with Darvyadi Churna 3gms once a day in morning on empty stomach with warm water for a period of 30 days. Subjective Parameters were analysed using paired sample t test. Result: Among 35 registered subjects, 30 completed the trial. After 30 days of intervention, significant improvements were observed in fasting blood sugar (FBS) (34.9% reduction, p<0.0001) and postprandial blood sugar (PPBS) (31.7% reduction, p<0.0001). The results suggest that Darvyadi Churna is an effective Ayurvedic intervention for managing Prameha and its associated symptoms. Conclusion: Darvyadi Churna is effective in the management of Prameha (Type 2 DM).

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