World Journal of Pharmaceutical
and Medical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology
An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)
ISSN 2455-3301
IMPACT FACTOR: 6.842

ICV : 78.6

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Abstract

ANTIBACTERIAL PROPERTIES OF METHANOL AND AQUEOUS EXTRACTS OF ANOGEISSUS LEIOCARPUS AND TERMINALIA MICROPTERA AGAINST SELECTED ORAL PATHOGENS

Amuda Oladunni*, Samuel Alimi Garba, Galadima Musa, and Jigam Ali Audu

ABSTRACT

In Africa, chewing sticks are commonly used for maintaining oral hygiene. Phytochemical contents and antibacterial activity of aqueous and methanol extracts of Terminalia microptera and Anogeissus leiocarpus were investigated using standard methods. Qualitative phytochemical screening of the two extracts of T. microptera and A. leiocarpus revealed the presence of all the tested phytochemicals. except anthraquinones, steroids and terpenoids which are absent in aqueous extract of A. leiocarpus. Quantitative phytochemical analysis (mg/100g) indicates the presence of phenols, flavonoids, tannins, saponins and alkaloids at concentration ranging from 805.231±10.83-880.393±6.05, 295.661±100.32-337.556±3.67, 142.321±12.62-253.25±8.56.63, 4.254±0.10-7.338±0.84 and 85.762±10.21-134.231±8.63 respectively. The antibacterial activity of the aqueous and methanol extract of the plants at 20, 30 and 40mg/mL revealed a spectrum of activity which is significant at p

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