ORAL VORICONAZOLE CAUSING SEVERE HYPOKALEMIA, ACUTE QUADRIPLEGIA AND PROLONGED QT INTERVAL: A RARE CASE REPORT
Dubey AP*., Viswanath S., Suhag V., Pathak A., Rathore A., Kapoor A.
ABSTRACT
Antifungal agents of the azole family have long been described as potentially arrythmogenic. Voriconazole is a broad spectrum antifungal in the azole family, with excellent bioavailability, both orally and intravenously. Hypokalemia is an uncommon side effect of oral voriconazole therapy. We present a case of young patient of haematological malignancy, who was started on empirical oral voriconazole therapy which resulted in severe hypokalemia, causing long QT interval and flaccid quadriparesis.
[Full Text Article] [Download Certificate]