Abstract

Dr. Yasir Abdalla Hussein Hakim*, Kanan Sanorhi, Asad Adam Abass, faiez Yousif, Abubaker Talha, Adil Khalil

ABSTRACT

Background: Dyslipidemia is one of the major risk factors for cardiovascular disease in diabetes mellitus. The characteristic features of diabetic dyslipidemia are a high plasma triglyceride concentration, low high density lipoprotein cholesterol concentration and increased concentration of small dense low density lipoprotein-cholesterol particles. Objective: The purpose of this study is was to determine the lipid Profiles in Sudanese patients with type 2 diabetes mellitus. Materials and Methods: The subjects of study were the adult type 2 diabetic patients (80) of both cases and control attending the Centre. The study included 80 Sudanese patients; half of them with type 2 diabetes mellitus (cases) and the rest are non-diabetics (control group). Venous blood samples were taken from all after at least 10 hours fasting for determination of serum level of cholesterol, triglycerides, high density lipoprotein and low density lipoprotein. Glucose level was also measured. Cases and controls were compared in all measures above looking for the differences. Result: in cases fasting blood glucose, high density lipoprotein, low density lipoprotein, triglyceride, total cholesterol, were found to be 87.5% (35 cases), 64.5% (28 cases), 77.5% (31 cases), 50% (20 cases), 32.5% (17 cases) respectively. In control group, fasting blood glucose, high density lipoprotein, low density lipoprotein, triglyceride, total cholesterol were found to be 100% (40 cases), 100% (40 cases), 100% (40 cases), 100% (40 cases), 100% (40 cases) respectively. Conclusions: The study revealed that the prevalence of dyslipidemia among Sudanese type 2 diabetic patients is remarkably increasing compared to non-diabetic control group.