METABOLIC ANALYSES OF NODDING SYNDROME IN UGANDA: A PILOT STUDY IS A BIOTINIDASE AND ACETYL CARNITINE DEFICIENCY; A METABOLIC DISORDER. AN OBSERVATIONAL STUDY DESIGN
Anywar Arony Denis, Peter Galloway, Angwech Collines, Makumbi Edward Frederick and
*Dr. Prof. Kitara Lagoro David
ABSTRACT
Background: Nodding Syndrome (NS) is a childhood neurological disorder which presents with a “head nodding”, cognitive decline, wasting, stunting and school dropout. We conducted a metabolic analysis on NS children receiving treatment at Hope for HumaNs (HfH) rehabilitation centre in Gulu, Uganda. Methods: We conducted a biochemical analysis on 48 NS children’s blood and urine samples collected in 2014 as part of a pilot study. Ethical approval was obtained from Lacor IRB and STATA was used for data analysis. A p-value of
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