Abstract

Dr. Amit Kumar*, Dr. V. N. Jha and Dr. Nimisha

ABSTRACT

Introduction: Megaloblastic anaemia is a general term used to describe a group of anaemias caused by impaired DNA synthesis. Megaloblastic anaemia is not uncommon in India, but data are insufficient regarding its prevalence, and causative and precipitating factors. We did a retrospective and prospective study to document such data for patients of megaloblastic anemia. Aims and objectives: To study the prevalence of megaloblastic anemia, its causative and precipitating factors and lastly its treatment. Material and methods: Approx. 400 patients admitted were investigated for megaloblastic anemia, their presenting complain, age of presentation, sex incidence, their dietary habits, etc. Results: Most of patients diagnosed as megaloblastic anemia were deficient in cobalamin and most were vegetarian. Conclusion: Megaloblastic anemia is relatively underdiagnosed cause of anemia. Treatment is very simple, affordable their in time treatment is important to prevent development of irreversible neurological complications.